FDA staff flag likely dosing errors with Purdue’s opioid painkiller

A view shows the U.S. Food and Drug Administration (FDA) headquarters in Silver SpringU.S. Food and Drug Administration staff have expressed concerns over likely errors in administering Purdue Pharma's fast-acting oxycodone painkiller that could result in inadequate relief. The drug is designed to be taken every 4-6 hours on an empty stomach as the absorption of oxycodone from the drug can be substantially delayed in the presence of food, studies have shown. This "food effect" may reduce the effectiveness and safety of the drug, to be called Avridi, FDA reviewers have said.



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